Dieter Hörsch Selected Research

telotristat ethyl

1/2022	Long-Term Treatment with Telotristat Ethyl in Patients with Carcinoid Syndrome Symptoms: Results from the TELEPATH Study.
3/2021	Time to Sustained Improvement in Bowel Movement Frequency with Telotristat Ethyl: Analyses of Phase III Studies in Carcinoid Syndrome.
1/2019	Long-Term Safety Experience with Telotristat Ethyl Across Five Clinical Studies in Patients with Carcinoid Syndrome.
12/2018	Relationship Between Symptoms and Health-related Quality-of-life Benefits in Patients With Carcinoid Syndrome: Post Hoc Analyses From TELESTAR.
1/2018	Telotristat ethyl in carcinoid syndrome: safety and efficacy in the TELECAST phase 3 trial.
1/2018	Changes in Weight Associated With Telotristat Ethyl in the Treatment of Carcinoid Syndrome.
11/2017	Understanding the Patient Experience with Carcinoid Syndrome: Exit Interviews from a Randomized, Placebo-controlled Study of Telotristat Ethyl.
1/2017	Telotristat Ethyl, a Tryptophan Hydroxylase Inhibitor for the Treatment of Carcinoid Syndrome.

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Dieter Hörsch Research Topics

Disease

18	Neuroendocrine Tumors (Neuroendocrine Tumor) 11/2021 - 01/2005
16	Neoplasms (Cancer) 01/2021 - 01/2005
11	Carcinoid Tumor (Carcinoid) 01/2022 - 12/2011
9	Diarrhea 01/2022 - 02/2011
3	Nausea 01/2018 - 02/2011
3	Flushing 01/2018 - 01/2015
2	Primitive Neuroectodermal Tumors (PNET) 01/2022 - 11/2021
2	Fatigue 12/2011 - 02/2011
1	Neuroendocrine Carcinoma 03/2022
1	Acromegaly 01/2019
1	Leukemia 03/2018
1	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 03/2018
1	Weight Loss (Weight Reduction) 01/2018
1	Weight Gain 01/2018
1	Abdominal Pain (Pain, Abdominal) 01/2018
1	Sleep Initiation and Maintenance Disorders (Insomnia) 12/2016
1	Disease Progression 12/2016
1	Heart Valve Diseases (Valvular Heart Disease) 04/2015
1	Angiomyolipoma 01/2013
1	Carcinogenesis 01/2013
1	Renal Cell Carcinoma (Grawitz Tumor) 01/2013
1	Breast Neoplasms (Breast Cancer) 01/2013
1	Astrocytoma (Pilocytic Astrocytoma) 01/2013
1	Tuberous Sclerosis (Bourneville's Disease) 01/2013
1	Aneuploidy (Aneuploid) 09/2012
1	Neoplasm Metastasis (Metastasis) 09/2012
1	Stomatitis 12/2011
1	Exanthema (Rash) 12/2011
1	Asthenia 02/2011
1	Vomiting 02/2011
1	Thyroid Neoplasms (Thyroid Cancer) 01/2007
1	Endocrine Gland Neoplasms (Cancer, Endocrine) 01/2007
1	Vascular Diseases (Vascular Disease) 04/2006
1	Bone Resorption 04/2006
1	Vascular Calcification 04/2006
1	Gastro-enteropancreatic neuroendocrine tumor 01/2005

Drug/Important Bio-Agent (IBA)

10	Somatostatin (Somatotropin Release-Inhibiting Factor)IBA 01/2022 - 01/2015
8	telotristat ethylIBA 01/2022 - 01/2017
7	Radioisotopes (Radionuclides)IBA 01/2021 - 12/2009
7	Peptide Receptors (Peptide Receptor)IBA 01/2021 - 12/2009
5	Tryptophan HydroxylaseIBA 01/2019 - 01/2017
5	Somatostatin Receptors (Somatostatin Receptor)IBA 03/2018 - 11/2011
3	Serotonin (5 Hydroxytryptamine)IBA 01/2019 - 04/2015
3	Octreotide (Sandostatin)FDA LinkGeneric 01/2019 - 12/2011
3	Everolimus FDA Link 01/2015 - 12/2011
2	Streptozocin (Streptozotocin)FDA Link 01/2022 - 09/2012
2	Proteins (Proteins, Gene)FDA Link 07/2018 - 04/2006
2	SurvivinIBA 07/2018 - 01/2005
2	telotristatIBA 01/2018 - 04/2015
2	Pharmaceutical PreparationsIBA 11/2017 - 12/2011
2	Sunitinib (Sutent)FDA Link 12/2016 - 02/2011
2	Fluorouracil (Carac)FDA LinkGeneric 09/2012 - 01/2005
2	Tyrosine Kinase InhibitorsIBA 02/2011 - 01/2005
1	SynaptophysinIBA 03/2022
1	Chromogranin AIBA 03/2022
1	Dacarbazine (DIC)FDA LinkGeneric 11/2021
1	RamucirumabIBA 11/2021
1	Cholinergic Antagonists (Anticholinergics)IBA 01/2019
1	Loperamide (Imodium)FDA LinkGeneric 01/2019
1	Diphenoxylate FDA LinkGeneric 01/2019
1	Atropine FDA LinkGeneric 01/2019
1	AntibodiesIBA 07/2018
1	Hydroxyindoleacetic AcidIBA 01/2018
1	TransferasesIBA 01/2017
1	5-hydroxyindoleIBA 01/2017
1	Acetic Acid (Vinegar)FDA LinkGeneric 01/2017
1	TOR Serine-Threonine KinasesIBA 01/2013
1	Hormones (Hormone)IBA 01/2013
1	ErbB Receptors (EGF Receptor)IBA 01/2013
1	Protein Kinases (Protein Kinase)IBA 01/2013
1	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 01/2013
1	Biological ProductsIBA 12/2012
1	fluorodopa F 18IBA 12/2012
1	LigandsIBA 12/2012
1	Aurora KinasesIBA 09/2012
1	danusertibIBA 09/2012
1	Gallium-68IBA 11/2011
1	Cyclin EIBA 11/2008
1	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 01/2007
1	raf KinasesIBA 01/2007
1	CytokinesIBA 04/2006
1	OsteoprotegerinIBA 04/2006
1	InterleukinsIBA 04/2006
1	Interleukin-4 (Interleukin 4)IBA 04/2006
1	Mitogen-Activated Protein KinasesIBA 02/2005
1	Valine (L-Valine)FDA Link 02/2005
1	Glutamic Acid (Glutamate)FDA Link 02/2005
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2005
1	Phosphotransferases (Kinase)IBA 01/2005
1	Tyrosine (L-Tyrosine)FDA Link 01/2005
1	Ki-67 Antigen (Ki 67 Antigen)IBA 01/2005
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2005
1	Imatinib Mesylate (Gleevec)FDA Link 01/2005

Therapy/Procedure

14	Therapeutics 11/2021 - 12/2009
1	Drug Therapy (Chemotherapy) 11/2021
1	Renal Dialysis (Hemodialysis) 03/2018
1	Aftercare (After-Treatment) 03/2018
1	Precision Medicine 01/2014
1	Cell Transplantation 09/2012
1	Conservative Treatment 09/2012